What
is an allergy?
How is
an allergy diagnosed?
How is an
allergy treated?
How can
an allergic reaction be avoided?
Animal Dander
Bee Stings
Drug & Chemical
Dust Mite
Food
Latex
Mold
Pollen
Alternative
Medicine
What
is an allergy?
Allergy is defined as an abnormal, exaggerated
response by the body's immune system against a specific substance
that is inhaled, ingested or otherwise contacted. An allergic immune
reaction is also known as hypersensitivity. The immune system serves
as the body's defense mechanism against countless substances present
in the air we breathe, the food we eat and the things we touch.
The body's immune system has mechanisms built-in to recognize self
from non-self so that we only react to things that pose a danger
to our well-being. Sometimes, that recognition system goes haywire
and an over-stimulated or hypersensitive allergic reaction can occur.
People who have allergies have an abundance of an antibody called
IgE. Following IgE production, these antibodies travel to cells
called mast cells, which are particularly plentiful in the nose,
eyes, lungs, skin and gastrointestinal tract. The IgE antibodies
attach themselves to the surface of the mast cells and wait for
their particular allergen. Each type of IgE is specific for one
type of allergen only. That's why some people are only allergic
to cat dander (they only have the IgE antibodies specific to cat
dander) and others seem to be allergic to everything (they have
multiple types of IgE antibodies.) The next time an allergic individual
comes into contact with the allergens to which he or she is sensitive,
the allergens will be captured by the IgE. This initiates the release
of chemical mediators such as histamine and other chemicals from
the mast cells. These mediators produce the symptoms of an allergic
reaction, such as swelling of tissues, sneezing, wheezing, coughing
and other reactions.
As the allergic reaction continues, these newly released mediators
recruit other cells from the blood to that site, resulting in additional
allergic inflammation. Many symptoms of chronic allergic disease,
such as swelling, excessive mucous, and sensitivity to irritating
airborne pollutants, such as smoke and perfume, are the result of
tissue inflammation. Most of this inflammation is due to ongoing
exposure to allergens. Some immune systems amplify an allergic response
causing it to go on for days from a single exposure. These amplification
symptoms are more complex and often take the form of tiredness,
aches and pains, headache, congestion, and even flu-like symptoms.
Allergy is one of a group of medical problems that are referred
to as the atopic diseases. The following diagram represents the
three atopic diseases: allergies, asthma, and eczema, and their
strong but not exclusive correlation with one another.
This means that the genes causing each of these medical problems
are closely linked and tend to be inherited together. A family history
of allergies is the single most important factor that predisposes
a person to develop allergic disease. If one parent has allergic
disease, the estimated risk of the child to develop allergies is
nearly 50%. The child's risk grows to 70% if both parents have allergies.
However, the fact that a person has these genes does not indicate
that the disease will show itself in the lifetime of an individual.
For example, a child who develops eczema early in life is much more
likely to have asthma, food allergies and allergic rhinosinusitis.
An adult with allergic rhinosinusitis is more likely to eventually
develop asthma and various types of eczema. In both cases, while
the manifestation of multiple problems is likely, it is not guaranteed.
The correlation, however, helps scientists create strategies to
prevent the development of these conditions over a lifetime.
How
is an allergy diagnosed?
If you are allergic, you are reacting to a
particular substance such as a pollen, dust mite, mold, food, chemical,
etc. Any substance that can trigger an allergic reaction is called
an allergen. To determine which specific substances are triggering
your allergies, your allergist/immunologist will safely and effectively
test your skin or sometimes your blood, using tiny amounts of commonly
troublesome allergens. The allergen extracts or vaccines used in
allergy tests are made commercially and are standardized according
to U.S. Food and Drug Administration (FDA) requirements. Your allergist/immunologist
is able to safely test you for allergies to substances using these
allergen extracts.
Allergy tests are designed to gather the most specific information
possible so your doctor can determine: (1) if you have an allergy;
(2) what you are allergic to; and (3) what will provide the best
treatment.
The testing methods approved by the FDA to diagnose allergies are
specific skin and blood tests. Both tests measure the same allergy
antibody but the skin test is more accurate, cost effective, and
sensitive for people over the age of approximately 5 years.
There are several scientifically proven allergy testing techniques
that are used by trained allergist/immunologists:
Prick technique involves introducing a small amount of allergen into the skin by
making a small scratch through a drop of the allergen extract. If
you have an allergy, the specific allergens that you are allergic
to will cause a chain reaction to begin on your skin and you will
get a small itchy welt at the site of the scratch. This will develop
over about 15 minutes and then slowly resolve over another 30 minutes,
so you don't have to wait long to know the results. There is a negligible
risk of the reaction affecting other areas of your body. People
with allergies have an allergic antibody called IgE (immunoglobulin
E) in their body. This chemical, which is only found in people with
allergies, activates special cells called mast cells. These mast
cells release chemicals called mediators such as histamine, the
chemical that causes redness and swelling. With testing, this swelling
occurs only in the spots where the tiny amount of allergen to which
you are allergic has been introduced. So, if you are allergic to
grass pollen but not to cats, the spot where the ragweed allergen
touched your skin will swell and itch a bit, forming a small dime-sized
hive. The spot where the cat allergen scratched your skin will remain
normal. This reaction occurs and tends to resolve within your body
quickly.
Intradermal technique involves injecting a small amount of allergen under the skin with
a syringe. This form of testing is more responsive than the prick
skin test method. This form of allergy testing may be used if the
prick skin tests are negative. Allergist/immunologists generally
only use this technique in adults. These tests are read in the first
15 minutes and then over the next 48 hours by the patient, recording
results on a Skin
Test Reaction Record.
Blood (RAST) test called a radioallergosorbent (RAST) test are sometimes performed.
Since this test involves drawing blood, it costs more, and the results
are not available as rapidly as skin tests. RAST tests are generally
used only in cases in which skin tests cannot be performed, such
as on patients taking certain medications, in children under the
age of 5 years, or those with skin conditions that may interfere
with skin testing.
Patch test involves placing a chemical or food on your skin under a small piece
of tape and leaving it there for 48 hours before removing it. The
tests are read at 48 hours and then checked daily by the patient
for about a week.
Challenge test involves introducing small amounts of the suspected allergen orally,
by inhhalation or other route. Challenges are rarely performed,
with the exception of medication and food
testing. When they are performed, they must be closely supervised
by an allergist/immunologist in the office or hospital.
How
is an allergy treated?
There are three primary scientific ways to
treat allergies: allergen immunotherapy, allergy medications and allergen avoidance.
Allergen Immunotherapy
Allergen immunotherapy is a natural form of
treatment using the body's own natural defenses to decrease your
sensitivity to substances called allergens. These allergens are
identified by allergy testing and corroborated by your medical history
as the substances that trigger your allergy symptoms after exposure.
Allergy immunotherapy is a proven effective treatment for allergic
rhinosinusitis, allergic asthma, and stinging insect allergy. It
also may be effective in some individuals with atopic dermatitis (eczema) if they have allergies to airborne allergens. Immunotherapy can
potentially modify the allergic disease leading to lasting remission
of allergy symptoms. Immunotherapy may play a preventive role in
pediatric allergic disease, in terms of development of asthma and
new allergies, thus early involvement of the allergy specialist
may be important in the child
with allergy symptoms.
Not only does immunotherapy naturally resolve most allergy problems,
it has been shown to prevent the development of new allergies and,
in children and adults, can prevent the progression of the allergic
disease from allergic rhinosinusitis to asthma.
Allergy is one of a group of medical problems scientists call atopic
diseases, that also includes asthma and eczema. The genes that cause
each of these medical problems are closely linked and tend to be
inherited together. For example, an adult with allergies is more
likely to eventually develop asthma and various types of eczema.
Allergen immunotherapy involves injecting increasing amounts of
natural allergen mixed in water each week over several months until
a certain general level of injection strength is reached. From that
point forward, the same injection dose is repeated every two to
four weeks for three to eight years. Allergen immunotherapy works
like a vaccine. Your body responds to the injected amounts of a
particular allergen, given in gradually increasing doses, by developing
an immunity or tolerance to the allergen that counters the allergic
response. Benefit is achieved rapidly, although several years of
regular treatment is necessary to create a memory so that the improvement
is lasting. The majority of allergy symptoms are resolved using
this method of treatment and its effect is long lasting even after
the injections are stopped. Allergen immunotherapy usually leads
to the long-lasting relief of allergy symptoms for a lifetime after
treatment is stopped provided a full course of treatment has been
completed.
There are generally two phases to immunotherapy: a build-up phase
and a maintenance phase.
Build-up
phase involves receiving injections with increasing amounts
of the allergens. The frequency of injections during this phase
generally ranges from one to two times a week, though more rapid
build-up schedules are sometimes used. The duration of this phase
depends on the frequency of the injections but generally ranges
from four to six months. At any time during the build-up phase you
can skip up to four to six weeks and pick up where you left off
in your schedule. Even if you don't receive an injection for more
than six weeks, you can return to a previous dose and continue on
from there.
Maintenance phase begins when the effective therapeutic dose is reached. The effective
maintenance dose is different for each person depending on the level
of allergen sensitivity (how allergic he or she is to the allergens
in the vaccine) and the response to the immunotherapy build-up phase.
Once the maintenance dose is reached, there will be longer periods
of time between immunotherapy treatments. The interval between maintenance
immunotherapy injections generally ranges from two to six weeks.
Based on the complexity of your allergy and your response, your
allergist/immunologist will decide what range is best for you.
The benefits of immunotherapy, in terms of
reduced allergy symptoms, can begin during the build-up phase but
may take as long as 12 months to begin. Improvement with immunotherapy
is commonly progressive throughout the treatment period but is most
dramatic during the first one to three years. Effectiveness of immunotherapy
appears to be related to length of treatment and the dose of the
allergen. Failure to respond to immunotherapy may be due to several
factors including:
Inadequate dose
of allergen in the allergy vaccine
Missing allergens not identified
during the allergy evaluation
High levels of allergen in
environment (i.e. inadequate environmental control)
Significant exposure to non-allergic
triggers (i.e. tobacco smoke)
If there is no improvement after a year of
maintenance immunotherapy, possible reasons for failure to respond
should be explored. If no apparent reason is found, then discontinuation
of immunotherapy should be considered and other treatment options
pursued.
Immunotherapy is only recommended for allergic asthma, stinging
insect allergy, allergic rhinosinusitis and conjunctivitis. Immunotherapy
for food allergies and contact skin allergies is not recommended.
The best option for people with food allergies is strict food avoidance.
The decision to begin immunotherapy will be based on several factors
including:
Length of allergy
season, complications from the allergy, and severity of symptoms
How well medications and/or
environmental controls manage allergy symptoms
Desire to avoid long-term
medication use through a natural drug-free treatment regimen
Time commitment; immunotherapy
will require a commitment of at least three years and optimally,
at least five years
Cost; immunotherapy is a cost
effective form of treatment after the first two to three years
The youngest age recommended to start immunotherapy
in the United States is five years of age for several reasons; including
the difficulty younger children may have in cooperating with the
immunotherapy program. Recent studies have suggested immunotherapy
may prevent the development of new allergies in children and also
may prevent the development of asthma when rhinosinusitis is present. There is no upper age limit for
receiving immunotherapy. In considering immunotherapy for older
persons, consideration must be given to the other medical conditions
(such as cardiac disease) which could potentially make immunotherapy
more risky.
Because allergy injections are a natural allergen mixed in water,
they are safe for administration to all age groups, including children
and pregnant
and breast feeding women.
There are two types of adverse reactions that occur with immunotherapy:
Local reactions are fairly common and present as redness and swelling at the injection
site. This can happen immediately, or several hours after the treatment.
Usually no treatment is required except cold compresses, antihistamines
and ibuprofen.
Systemic reactions are generalized allergy reactions that are much less common than
local reactions. Systemic reactions are usually mild and respond
rapidly to medications or just spontaneously resolve. Symptoms can
include increased allergy symptoms such as sneezing, nasal congestion
or hives. Systemic reactions require immediate treatment and are
usually quickly reversible.
Rarely, a serious life-threatening systemic
reaction, called anaphylaxis, can develop after an immunotherapy
injection. In addition to the symptoms associated with a mild systemic
reaction, symptoms of an anaphylactic reaction can include swelling
in the throat, wheezing or a sensation of tightness in the chest,
nausea, dizziness or other symptoms and even death.
Most serious systemic reactions develop within 30 minutes of the
allergy injections and this is why it is recommended you wait in
the office for 30 minutes after your allergy injections. Our office
staff is trained to monitor for such reactions and to identify and
treat systemic reactions.
Immunotherapy should be given under the supervision of a physician
in a facility equipped with proper staff and equipment to identify
and treat adverse reactions to allergy injections. Ideally, immunotherapy
should be given in our office. If this is not possible we can provide
comprehensive instructions about your immunotherapy treatment to
another supervising physician.
Allergy Medications
Oral and
Nasal Antihistamines block histamine, one of the most important
mediators of the allergic response. They can be effective in some
forms of non-allergic rhinosinusitis, but not always. They are also
more effective for seasonal allergic rhinosinusitis, in contrast
to perennial allergic rhinosinusitis. The release of histamine leads
to many allergy symptoms, including itching of the eyes and nose,
runny nose and sneezing. It is important to understand that antihistamines
block the receptor sites in the body for histamine. Therefore, taking
the antihistamine after an allergy has started is like closing the
barn door after the horse has run out. It may stop the other horses
from getting out but the first event has already occurred. Like
any allergy medication, these drugs are best taken before, or in
anticipation of, an allergic reaction to be most effective.
Nasal inhaled corticosteroids reduce and control the impact of all or most of the mediators that
can cause inflammation in the nose. It improves the nasal symptoms
of allergic rhinosinusitis, including itching, runny nose and congestion.
These medications take three to five days to become maximally effective.
Decongestants are important in the care of many forms of rhinitis because congestion
is, for the many patients with rhinitis, a troublesome symptom.
Antihistamines do not do a very good job with nose stuffiness at
all times. Sudafed is the most active medication available currently
for the treatment of stuffiness. It should be emphasized that this
medication can make sleeping difficult and in some men make urination
difficult. Therefore, the use of this medication should be carefully
adjusted to your needs and tolerance. If a D is added to your antihistamine
name, it is essentially Sudafed.
Leukotriene modifiers block the action of leukotrienes, a mediator of allergy symptoms
and of inflammation. They block both the early response to allergic
triggers (itching and sneezing) as well as the delayed response
to allergic triggers (congestion). Overall, they are not as effective
as antihistamines and nasal steroids in controlling allergy problems
as single agents.
How
can an allergic reaction be avoided?
Allergen avoidance techniques vary depending
on the type of allergen you react to. Many allergens have a seasonal
presence, in which case special care must be taken during certain
times of the year.
Animal Dander
The most effective method of reducing exposure
to household pet allergens is to find your pet a new home or make
the pet an exclusive outdoor animal. If a pet must stay in the home
at times or continuously:
Designate a safe
room (such as a bedroom) with a closed door where the pet never
enters.
Vacuum thoroughly and often
with a HEPA vacuum or a machine equipped with a high-efficiency
bag.
Wash the pet weekly to help
reduce allergen shedding.
Use high-efficiency or electrostatic
filters over air vents to reduce airborne pet allergens. A room
air cleaner with a high-efficiency filter will reduce airborne pet
allergens very little unless other measures have been taken.
Bee Stings
To avoid stinging insects, it is important
to learn what they look like and where they live. Most sting reactions
are caused by five types of insects: yellow jackets, honeybees,
paper wasps, hornets and fire ants.
Yellow jackets are black with yellow markings,
and are found in various climates. Their nests, which are made of
a paper-like material, are usually located underground, but can
sometimes be found in the walls of frame buildings, cracks in masonry
or woodpiles.
Honeybees have a rounded, fuzzy body with dark brown coloring
and yellow markings. Upon stinging, the honeybee usually leaves
its barbed stinger in its victim; the bee dies as a result. Honeybees
are not aggressive and will only sting when provoked. However, Africanized
honeybees, or so-called "killer bees" found in the southwestern
United States and South and Central America, are more aggressive
and may sting in swarms. Domesticated honeybees live in man-made
hives, while wild honeybees live in colonies, referred to as honeycombs,
in hollow trees or cavities of buildings. Africanized honeybees
may nest in holes in house frames, between fence posts, in old tires
or holes in the ground, or other partially protected sites.
Paper wasps have slender, elongated bodies that
are black, brown, or red with yellow markings. Their nests are also
made of a paper-like material that forms a circular comb of cells
which opens downward. The nests are often located under eaves, behind
shutters, in shrubs or woodpiles.
Hornets are black or brown with white, orange or
yellow markings and are usually larger than yellow jackets. Their
nests are gray or brown, football-shaped, and made of a paper-like
material similar to that of a yellow jackets nest. Hornet nests
are usually found high above ground on branches of trees, in shrubbery,
on gables or in tree hollows.
Fire ants are reddish brown to black stinging insects
related to bees and wasps. They build nests of dirt in the ground
that may be quite tall (18 inches) in the right kinds of soil. Fire
ants may attack with little warning: after firmly grasping the victim's
skin with its jaws, the fire ant arches its back as it inserts its
rear stinger into the skin. It then pivots at the head and may inflict
multiple stings in a circular pattern. Fire ant venom often causes
an immediate burning sensation.
Stay away from the nests of stinging insects.
These insects are most likely to sting if their homes are disturbed,
so it is important to have hives and nests around your home destroyed
by a professional. Since this activity can be dangerous, a trained
exterminator should be hired.
If you encounter any flying stinging insects, remain calm and quiet,
and move slowly away from them. Many stinging insects are foraging
for food, so don't look or smell like a flower (e.g. avoid brightly
colored clothing and perfume when outdoors). Because the smell of
food attracts insects, particularly yellow jackets, be careful when
cooking, eating, or drinking sweet drinks like soda or juice outdoors.
Keep food covered until eaten. Wear closed-toe shoes outdoors and
avoid going barefoot. Also, avoid loose-fitting garments that can
trap insects between material and skin.
If you are stung by a honeybee that has left its stinger (and attached
venom sac) in your skin, remove the stinger within 30 seconds to
avoid receiving more venom. A quick scrape of a fingernail removes
the stinger and sac. Avoid squeezing the sac because this forces
more venom through the stinger and into the skin. Hornets, wasps,
and yellow jackets do not usually leave their stingers. Try to remain
calm, and brush these insects from the skin promptly with deliberate
movements to prevent additional stings. Then, quietly and immediately
leave the area.
If you are stung by fire ants, carefully brush them off to prevent
repeated stings, and leave the area. Fire ant stings usually result
in the development of a blister about 24 hours after the sting.
The material in this will become cloudy and appear to be infected,
but it is not. Fire ant venom kills bacteria. This is just dead
tissue and should be left alone. It will dry and heal within the
next seven to 10 days. If the blister is open it must be monitored
for secondary bacterial infection. Diabetics and others with circulatory
disorders, including varicose veins and phlebitis, can be particularly
at risk for complications, and should see a physician to monitor
their condition after being stung. Up to 50% of patients develop
large local reactions at the site of fire ant stings. Swelling may
last for several days and may be accompanied by itching, redness
and pain.
Taking the following steps can help in treating local reactions
to insect stings:
Elevate the affected
arm or leg and apply ice or a cold compress to reduce swelling and
pain.
Gently clean blisters with
soap and water to prevent secondary infections; do not break blisters.
Use topical steroid ointments
or oral antihistamines to relieve itching.
See your doctor if swelling
progresses or if the sting site seems infected.
If you are severely insect-allergic and have
had prior reactions, carry one or, preferably, two auto-injectable
epinephrine (adrenalin) devices, a short-term treatment for severe
allergic reactions. Learn how to self-administer the epinephrine
according to your allergist/immunologist's instructions and replace
the device before the labeled expiration date.
Remember that injectable epinephrine is rescue medication only.
If you are allergic and are stung you must still have someone take
you to an emergency room immediately. Additional medical treatment
may be necessary. Those with severe allergies should consider wearing
a special bracelet or necklace that identifies the allergy and supplies
other important medical information in case of an emergency.
People who have systemic allergies to insect venom should always
consider receiving insect venom immunotherapy, a highly effective
vaccination program that actually prevents future allergic sting
reactions in 97% of treated patients. During immunotherapy, our
office administers gradually stronger doses of natural venom extract
initially every week for about 10 weeks. As maintenance doses are
reached the interval between injections is expanded to one month
or more. The treatment program generally lasts for five years at
which time most people can stop immunizations and still maintain
permanent immunity from life-threatening allergic reactions to bee
stings. Patients who receive appropriate treatment, such as immunotherapy,
and who practice careful avoidance measures can participate in regular
outdoor activities and lead a normal life.
Drug & Chemical
Any allergy to a drug or chemical, whether
encountered as a food or medication or exposed topically in a cream
or ointment, is treated with avoidance. Your allergist/immunologist
will help you identify the drug or chemical you are allergic to,
understand where that drug or chemical is found and what other drugs
or chemicals might be cross-reactive. Identifying a drug or chemical
allergy is very difficult because the testing materials available
are very limited. An accurate and carefully obtained history is
of utmost importance in identifying a drug or chemical allergy.
There are no blood tests for drug or chemical allergies. However,
there is a skin test available called patch testing that can be
used to help identify some chemical or drug allergies. In patch
testing, the chemical in question is simply applied to the skin
in vaseline with a bandaid-like tape and left for 48 hours before
reading.
Dust Mite
House dust allergy is caused by house dust mites and their allergens. Dermatophagoides farinae and dermatophagoides pteronyssinus are the two know species. House dust mites thrive in humidity above
50% and are frequently found in pillows, mattresses, and upholstered
furniture. The highest concentration of house dust mite is found
in the bedroom. Given that an average person spends a third or more
of his life in the bedroom, dust mite avoidance can be difficult.
It is virtually impossible to avoid house dust mites completely.
However, there are measures you can take to limit your exposure:
Encase pillows
and mattresses in allergen-impermeable covers. These covers come
in four varieties; plastic, polyurethane-coated, tight-woven, and
non-woven fabrics. The tight woven type of cover is generally the
most effective and comfortable.
Wash sheets and blankets weekly
in hot water (greater than 130 degrees F).
Remove carpets. If carpets
can't be removed, keep them clean by vacuuming weekly with a high-efficiency
particulate air (HEPA) vacuum, or use a high-efficiency vacuum bag.
Treating them with a powder or spray that helps control dust mites
or their allergens is generally not recommended due to poor effectiveness
and possible toxicity from the chemicals used.
Avoid lying or sleeping on
upholstered furniture.
Minimize the number of stuffed
toys in the home. If stuffed toys are present in the household,
wash them weekly (if machine-washable) at over 130 degrees F, or
freeze them in a sealed plastic bag for 24 hours. Both methods will
kill dust mites.
Control humidity levels and
dampness by using air conditioners and dehumidifiers. Ideally, keep
the humidity level below 50%. You can buy a very inexpensive hygrometer
at the hardware store that measures humidity. If your humidity is
frequently above 50%, that means you have some water leakage problems
or you need to air out your home more regularly. Outdoor humidity
is rarely that high unless it is raining or foggy.
When cleaning and vacuuming,
wear a mask so that allergens stirred up do not further aggravate
symptoms. If possible, severe allergy sufferers should let others
do the vacuuming.
Food
Food allergens, those parts of foods that
cause allergic reactions, are usually proteins. Most of these allergens
can still cause reactions even after they are cooked or have undergone
digestion in the intestines. Numerous food proteins have been studied
to establish allergen content.
There
are many foods known to cause an allergic reaction: |
FRUIT |
Apple,
Banana, Cantaloupe, Juniper Berry, Mango, Orange, Peach, Raspberry,
Strawberry, Tangerine |
VEGETABLES |
Artichoke, Beet,
Celery, Corn, Mushroom, Potato, Sweet Potato
|
LEGUMES |
Castor Bean,
Garbanzo Bean, Lentil, Lima Bean, Pea, Soybean
|
NUTS |
Almond, Brazil,
Cashew, Chestnut, Coconut, Filbert, Peanut, Pine, Walnut,
Pistachio
|
SEEDS |
Anise, Caraway,
Cottonseed, Cumin, Dill, Fennel, Flax, Poppy, Psyllium, Sesame,
Sunflower
|
SPICE & HERB |
Allspice, Bay
Leaf, Black Pepper, Chamomile, Chicory, Chili Pepper, Cinnamon,
Clove, Garlic, Ginger, Horseradish, Nutmeg, Mustard, Sage,
Thyme, Turmeric, Vanilla
|
FISH & SHELLFISH |
Clam, Cod, Crab,
Cuttlefish, Halibut, Lobster, Salmon, Shrimp
|
MEAT & POULTRY |
Chicken
|
DAIRY |
Milk
|
GRAIN |
Buckwheat, Hops,
Millet, Tapioca, Wheat
|
MISC |
Baker's Yeast,
Brewer's Yeast, Chocolate, Egg, Honey
|
The most common food allergens, responsible
for up to 90% of all allergic reactions, are the proteins in cow's
milk, eggs, peanuts, wheat, soy, fish, shellfish and tree nuts.
All foods come from either a plant or an animal source, and foods
are grouped into families according to their origin. For example,
peanuts, black-eyed peas, kidney and lima beans, and soybeans are
some of the members of the legume family, whereas asparagus, chives,
garlic and onion are, surprisingly, members of the lily family.
In some food groups, especially tree nuts and seafood, an allergy
to one member of a food family may result in the person being allergic
to all members of the same group. This is known as cross-reactivity.
However, some people may be allergic to both peanuts and walnuts,
which are from different food families; these allergies are called
coincidental allergies, because they are not related. Within animal
food groups, cross-reactivity is not as common. For example, people
allergic to cow's milk can usually eat beef, and patients allergic
to eggs can usually eat chicken. With shellfish, crustaceans (shrimp,
crab and lobster) are most likely to cause an allergic reaction.
Molluscan shellfish (clam, oysters, abalone, etc.) can be allergenic,
but reactions to these shellfish are less common.
Sometimes food intolerance is confused with food allergy. Food intolerance
reactions are usually caused by factors in the diet other than the
proteins that make up food allergens. One of the most common is
lactose intolerance. Other food intolerance reactions may be triggered
by drug-like chemicals in some foods. Symptoms can include nervousness
after consuming caffeine in coffee or soft drinks, headaches triggered
by chemicals in cheese and chocolate, or various adverse reactions
to chemicals and preservatives added to food, called food
additives. These additives may cause adverse reactions in sensitive
people. The most common food additives that may cause reactions
include benzoates, BHA and BHT, FD&C dyes Yellow No. 5 and Red No.
3, monosodium glutamate (MSG), nitrates/nitrites, parabens and sulfites.
However, true allergic reactions to food additives are very rare.
True food allergic reactions can take on several forms. In some
cases, the reaction is limited to eczema flares. In others, severe stomach cramps and diarrhea can occur
or more generalized reactions, such as hives and even anaphylaxis,
are a result. If there is any anaphylaxis risk, injectable epinephrine
should be carried with you and you should wear a medical identification
bracelet at all times.
Take the following steps to avoid a food allergy reaction:
Avoid the
food. The best way to treat food allergy is to avoid the
specific foods that trigger the allergy. Look for recipes that specifically exclude the food you are allergic to.
Ask about ingredients.
To avoid eating a hidden food allergen away from home, food-allergic
individuals must always inquire about ingredients when eating at
restaurants or outside the home.
Read food labels.
It is important for food-allergic people to read food labels carefully
and to become familiar with technical or scientific names for foods.
For example, milk may not be listed as an ingredient on a label;
rather, the label may list casein (a milk protein), sodium caseinate
or milk solids. Not every food that contains wheat identifies it
as such; sometimes wheat is listed as gluten. Similarly, egg white
is frequently listed as albumin. Government agencies have been working
toward improving food ingredient labeling so food-allergic consumers
can more easily determine which foods they may need to avoid.
Be prepared for emergencies.
Anaphylactic reactions caused by food allergies can be potentially
life-threatening. Those who have experienced an anaphylactic reaction
to a food must strictly avoid that food. They may need to carry
and know how to use injectable epinephrine and antihistamines to
treat reactions due to accidental ingestion. People who are commonly
around the patient, such as spouses, co-workers, schoolteachers
or daycare workers, should also know to use the injectable epinephrine.
Those with food allergies should also wear an identification bracelet
that describes the allergy. If you have an anaphylactic reaction
after eating a food, it is essential that you have someone take
you to the emergency room, even if symptoms subside. For proper
diagnosis and treatment, make sure to get follow-up care from an
allergist/immunologist.
If you have food allergies, you may also contact
the Food Allergy and Anaphylaxis Network (FAAN) for support: (800)
929-4040 or www.foodallergy.org.
Eating Out With A Food Allergy
Food allergy sufferers know more than anyone that one wrong bite can turn a pleasant meal into an emergency room visit or a fatal outcome in some cases. Food allergic reactions vary from unpleasant gastrointestinal distress to life threatening anaphylaxis. Wheat, soy, milk, eggs, and peanuts are the most common food allergens in children. In adults, the list is expanded to include fish, shellfish and tree nuts. Some people have more diverse allergens that can be easily hidden in foods such as different kinds of seeds and spices.
The Food and Drug Administration advises that restaurant operators be aware of the major food allergens. However, there are no Federally mandated allergy safety guidelines for restaurants to follow. Avoiding problem foods and cross-contamination, such as French fries cooked in the same oil as shrimp or meat prepared on a surface where some nuts were recently chopped, requires effective communication between customers, servers and the kitchen staff. Some states such as Massachusetts, Michigan, Montana, New York, and North Caroline are trying to pass legislation related to food allergies and restaurants but, as most of you know, our country is encumbered with threats of lawsuits which can paralyze the legislative process.
There is no guarantee that a meal eaten at a restaurant will be allergen free for any given individual. However, the food allergy sufferer can increase the chances of having a pleasant meal out by following these important steps.
- Let your server know about your food allergy. If you feel there is a particularly high risk (fish allergy and you are eating in a fish restaurant or a soy allergy in a Chinese restaurant-not exactly a good idea), also let the manager know. Be prepared to be pushy. If your allergy is truly life threatening, as we often see with fish, shellfish, peanut and tree nut allergy, make sure the server knows that your death can be the consequence of their failure. This may sound harsh and, for some, an exaggeration. Nevertheless, it does get their attention.
- Ask about the kitchen’s procedures for avoiding cross-contamination. This also acts as a reminder to keep your food away from potentially hazardous ingredients. Some restaurants will use other kitchen tools or cook on foil to prevent cross-contamination which we feel is a good idea.
- Make sure the server checks with the chef and reports back to you that the food you ordered is free of your allergen before they start cooking. Sometimes servers are not as well informed about ingredients as the food allergy sufferer would like. Furthermore, menus change frequently and ingredient lists are often too voluminous for the server to maintain such expertise under all circumstances. The more the people involved in your food chain (server, manager, chef) are informed about your allergy, the safer your meal will be. Some chef’s do not speak english so make sure there is nothing lost in the translation if that is your suspicion.
- Know the hidden sources of your food allergen! Refer to the Food Allergy Network for details. For example, milk and wheat can be hidden in sauces and marinades and can be missed by the chef. Some restaurants use some processed foods. The labels from these foods must be individually checked by the chef or the manager to ensure your safety. Don’t be afraid to ask to see the label if you are worried.
Latex
Latex is a milky fluid produced by rubber
trees (hevea brasiliensis). Using different methods, latex can be
processed into a variety of products, such as gloves and balloons.
During manufacturing, chemicals are added to increase the speed
of curing (vulcanization) and to protect the rubber from oxygen
in the air.
Products made from blends of natural rubber latex and other compounds
are very common. In those with latex allergy, allergic reactions
are most often triggered by dipped latex products. Products that
commonly cause reactions can include gloves, balloons and condoms.
In rare instances, people who are allergic to latex may also react
to rubber bands, erasers, rubber parts of toys, various rubber components
in medical devices, rubber elastic in clothes, or feeding nipples
and pacifiers. Products molded from hard, crepe rubber, such as
soles of shoes, are unlikely to cause reactions. Nearly all latex
paints are problem-free since they do not contain natural rubber
latex.
Most people become allergic to latex due to high exposure such as
in the work environment (e.g. nurses, doctors, dentists dental hygienists)
or from undergoing long or repeated surgeries. The 1990 Americans
with Disabilities Act (ADA) covers people with severe allergies
to substances such as latex. If you are otherwise qualified but
can no longer work with latex in a job setting because of your allergy,
work with your employer to determine other options and make reasonable
accommodations. If you are allergic and need to wear gloves, or
are in contact with persons wearing gloves, there are several options:
(1) Try substituting synthetic (vinyl or nitrile) gloves for latex
gloves, although they may not work as well in some situations. These
work in nearly all situations in which latex gloves are used, including
surgery, but in some cases they are more expensive. (2) Try latex
gloves made without additional chemicals.
If you have significant latex allergy respiratory symptoms from
inhaling latex particles, you need to avoid areas where powdered
gloves are used frequently. Ideally, all high glove use areas should
use powder-free gloves to avoid allergic reactions. This usually
solves the airborne latex allergen problem.
Using latex condoms can be a severe problem for some latex-allergic
people. One option is natural skin condoms. These do not contain
latex and can prevent pregnancy, but they do not protect against
viruses like HIV, which cause AIDS, or some other sexually transmitted
diseases (STDs). Synthetic rubber condoms, created to prevent both
pregnancy and STDs, are now available.
Manufacturers are currently working to produce latex products that
contain less latex allergen. As these products become more available,
the risk of reactions in people sensitive to latex, as well as the
risk of more people developing latex allergy, should decrease.
Mold
There are many different types
of mold that grow almost anywhere. They can be found wherever
there is moisture, oxygen, and a source of nutrients suitable to
their particular needs. Outside, they grow on rotting logs and fallen
leaves, especially in moist, shady areas. In gardens, they can be
found in compost piles and on certain grasses and weeds. Often allergy
symptoms during lawn mowing are due to mold under the grass rather
than the grass itself. The thatch of a lawn is particularly rich
in mold. Some molds attack grains such as wheat and rice so that
barns, grain bins and silos are likely places to find molds. Hot
spots of mold growth in the home include damp basements and closets,
bathrooms (especially around showers, windows and the underside
of the toilet). Other problem areas are places where food is stored
such as refrigerators or a fruit bowl. Refrigerator drip pans, humidifiers,
and air conditioners, especially swamp coolers, are notorious sites
of mold contamination. Garbage pails, old mattresses and pillows,
upholstered furniture and wicker furniture are also favorite mold
homes. Avoidance of molds in the Sacramento Valley is virtually
impossible, but some measures can be taken to reduce exposure to
below an individual's threshold of sensitivity. For some sufferers
any mold is too much mold. For these individuals, moving to a low
mold climate such as the desert may be the only avoidance alternative.
The allergy sufferer should
avoid the hot spots mentioned earlier where molds tend to concentrate.
When avoidance is impossible, a tightly fitted disposable mask
or a mask equipped with a HEPA filter should be used. Your allergist/immunologist
can provide you with some guidelines for purchasing this equipment.
Travel in the country on dry windy days or during harvest should
be avoided. A summer cabin closed up all winter is probably full
of molds and should be aired out and cleaned before a mold-sensitive
person stays there.
Around the home, a dehumidifier
will help dry out damp areas, such as a basement, but water must
be removed frequently to avoid mold contamination. Humidity below
60% inhibits mold growth but humidity below 50% can make breathing
uncomfortable due to over-drying. A hygrometer can be purchased
for under $20 to help you monitor this situation. A HEPA filter
can be purchased for small rooms that are difficult to keep dry.
Central air conditioning and heating filters should be cleaned
regularly and a HEPA filter inserted into the air intake to maximize
efficiency. A room HEPA filter may be purchased individually for
areas lived in most, such as bedrooms, if desired.
Mold is often found in homes
that have had indoor water leaks or flood problems, such as roof
leaks, foundation cracks, water heater and plumbing leaks. To
remove mold from walls, use the following common household bleach
mixture to scrub away mold:
1. Dilute a non-abrasive
household cleaner with bleach and water.
2. Mix in a glass or plastic container,
NOT in metal.
3. Using rubber gloves scrub the walls
and tiles and remove all visible mold growth. Let dry 1-2 hours,
and then scrub again.
4. Rinse with water.
5. Washing the area first with a non-abrasive
cleaner such as Bon-Ami is helpful for heavily infested areas
in bathrooms and basements.
Repaint the wall. In bathrooms,
use marine paint and avoid wallpaper and carpeting. If mold is
found on the concrete slab, scrub as previously instructed before
replacing carpeting. Avoid do-it-yourself carpet cleaning using
water soaking steam-cleaning processes.
Healthy, indoor plants may
not contribute significantly to the mold problem, but wicker baskets
used with the plants can harbor molds. Mold in the plant soil
is released only if the soil is disturbed during watering or transplanting.
However, terrariums and large planters, especially if used in
the bathroom, can be constant mold sources.
Heat can help rid closets
of mold by leaving the light on for a day to a week. Moth preventatives
do not inhibit mold growth.
Use a Dacron-polyester pillow,
rather than foam or feather filled. Putting the pillow in the
dryer twice a week can control mold that may form in the pillow
because of perspiration.
Do not store firewood inside
the house or in the basement or garage.
Mold growing around the house can contribute
significantly to the indoor mold levels. Recommendations for reducing
outdoor mold sources are:
Prune and trim
large shrubs and trees to allow sunlight into the home and surround
areas.
Maintain your landscaping.
Remove dead leaves and other organic debris. Avoid compost, hay,
and heavy ground cover such as ivy.
Avoid using redwood and fir
bark chips. Instead use non-organic material such as lava rock or
stone.
Remove standing water and
correct areas of poor drainage.
If your plants appear diseased,
consult with a plant expert. Often diseases are caused by molds.
Pollen
For pollen to be allergenic, it must be airborne
and enter the respiratory tract. It is important to remember that
flowering plants have flowers to attract insects to do the pollination.
For this to occur efficiently, pollen from flowering plants must
be very sticky and heavy so that it moves with the insect. Rarely
does such pollen become airborne. Therefore, contrary to many comments
we hear, flowering plants are not very allergenic, if at all. It
is the non-flowering aeroallergenic
plants such as grass, oak trees, walnut trees, olive trees,
etc. that are the most allergenic and create havoc in the Sacramento
Valley. Virtually millions of pollen is released annually from these
and other non-flowering plants each spring, summer and fall. Even
in the winter, some pollen from conifer trees and, in January, from
alder trees, can be found. Because the northern Sacramento Valley
rarely, if ever, freezes we experience some pollen 12 months of
the year although the peak is in the spring from March to early
June. These airborne pollens can travel as much as 10 miles on a
windy day making avoidance very difficult.
The following general recommendations can be made to try and minimize
pollen exposure:
Stay indoors with
your windows closed during the time of year you experience your
allergies. If available, keep your air conditioning on, especially
during the midday and afternoon when pollen levels are high.
If you must be outside, do
your outdoor activities shortly after sunrise when pollen levels
are lower.
Machine-dry clothes or hand-dry
indoors. Hanging clothes outside to dry allows pollen to collect
on them.
Wash and dry your hair to
help remove pollen before lying down to sleep to keep pollen out
of your bedroom.
Use a HEPA filter in your
bedroom next to the head of the bed. At night, run the HEPA filter
on the silent fan so that a gentle breeze of clean air moves over
your head throughout the night. If you air out your bedroom in the
morning, close it up and run the filter on high for several hours
to clear the air before you spend more time in the room.
The northern Sacramento Valley is one of the
most allergenic areas in the United States. We can claim this because
we are agriculturally based, have an abundance of water, and have
a very temperate climate with a long growing season and little to
no freezing. In addition, we grow commercially two very allergenic
plants, walnuts and olives, which can cause extreme allergic reaction.
In addition, our most abundant indigenous tree is the highly allergenic
oak. Plush, green, warm areas with lots of lakes, rivers, and streams
are great to live in but are also great allergenic plant producers.
In reality, it is impossible to avoid pollen exposure without moving
to a lower allergenic climate such as the high mountains, desert
or ocean. For the majority of pollen allergy sufferers who cannot
move, all that is available for relief is medications during the
allergy season and immunotherapy, which can generally cure the majority
of your allergy symptoms naturally, but requires time.
Alternative
Medicine
There are many nontraditional and scientifically
unproven allergy tests that claim to diagnose your hidden allergies
and relieve your sneezing, congestion, headaches, tiredness and
wheezing. Collectively, these practices fall into the category of
complementary and alternative medicine (CAM).
On the surface, some CAM approaches for allergies may sound logical,
but all are based on unproven theories. To add to the confusion,
some of these approaches are promoted by medical professionals.
Most of these promoters are not board certified allergist/immunologists
and often not even medical physicians. Although CAM therapies may
help treat some conditions such as arthritis pain, no such evidence
exists for alternative tests and treatments that help allergies.
If you're considering a CAM approach for your allergies, you may
end up spending your time and money on ineffective and unsafe methods,
and delaying conventional treatment that may offer genuine relief.
Furthermore, some have been shown to be dangerous.
CAM practitioners base their allergy tests and treatments on controversial
theories about what causes allergies without any scientific foundation.
They claim that many substances, including those widely accepted
as causing allergy, play a role. Examples of such substances include:
Microorganisms
such as yeast (candida albicans)
Electromagnetic radiation
from power lines and electronic devices
Food additives such as dyes
and preservatives
Chemicals in products such
as cleaning solvents, paints and perfumes
Multiple foods, especially
milk, chocolate, corn and wheat
Molds
Your hormones, especially
progesterone
CAM practitioners typically cite anecdotal
case reports and clinical experience as evidence, but they haven't
proven that these substances cause an allergic reaction with any
scientific information. A person may develop symptoms after exposure
to a substance without necessarily being allergic to it. Nevertheless,
CAM proponents suggest that "allergies" to many different substances
cause a variety of diseases. None of these is a recognized allergic
condition:
Environmental
illness (multiple food and chemical sensitivities): Foods,
food additives and environmental chemicals, especially chemicals
found in cleaning solvents, paints, smoke, gasoline, perfume, and
office-machine fumes, are said to cause fatigue, headache, nausea,
dizziness and disorientation.
Candida hypersensitivity
syndrome (yeast hypersensitivity): Candida albicans,
a fungus that lives inside all humans, usually causes no problems
other than yeast infections. But CAM proponents claim that it's
responsible for allergies, arthritis, cancer and AIDS.
Attention-deficit/hyperactivity
disorder (ADHD): Although ADHD is a recognized medical
condition, CAM practitioners falsely claim that sensitivity to food
dyes, preservatives and other additives causes its characteristic
erratic behavior and inability to concentrate. Actual causes aren't
known, though family history and altered brain function may play
a role. Conventional doctors usually treat ADHD as a brain disorder.
Allergic toxemia (tension
fatigue syndrome): A cluster of common symptoms such as
fatigue, headache, abdominal pain, paleness and respiratory problems
are supposedly caused by allergies to multiple substances, especially
foods.
Complementary and alternative practitioners
claim their tests reveal allergies that conventional allergy tests
miss. These unconventional tests may include:
Antigen
leukocyte cellular antibody test (ALCAT): The practitioner
draws samples of your blood and exposes them to 150 to 200 different
extracts of foods, drugs, chemicals, pollen, mold and animal dander.
A computer analyzes changes in leukocytes, a type of blood cell.
If your blood cells flatten, fragment or disintegrate in response
to an extract, it's considered evidence of allergy.
Applied kinesiology
testing: In one hand, you hold a vial containing a suspected
allergen while the practitioner bends your opposite arm to measure
muscle strength. A decrease in strength is considered a sign of
allergy.
Cytotoxic testing: This test is similar to ALCAT. The practitioner draws samples of
your blood and exposes them to different extracts. The difference
is that a technician looks through a microscope for evidence of
cellular changes that indicate allergy.
Electrodermal testing: In one hand, you hold a negative electrode attached by a wire to
an aluminum plate. The practitioner adds vials of food extracts
to the plate. He or she then completes the circuit by probing various
points on your body with a positive electrode. Fluctuations in the
low-voltage electrical current supposedly indicate an allergy to
a particular food.
Skin endpoint titration
testing: You receive multiple injections, sometimes up
to nine, of increasingly high concentrations of suspected allergens
under your skin. If a wheal or welt appears, it's considered evidence
of an allergy.
These tests may seem sophisticated, and may
superficially resemble the standardized skin and blood tests your
allergy specialist uses. However, in truth, there are no controlled
clinical trials that show they can convincingly diagnose any allergic
conditions. Furthermore, positive tests to many of these approaches
can be found in perfectly healthy normal people who do not have
any allergies.
No matter how elaborate a CAM theory may be, it likely won't lead
to treatments that relieve your allergies. No convincing evidence
suggests that CAM treatments are safe and effective for allergic
disorders. In fact, some may harm you or make your allergies worse.
For example:
Antifungal treatments: If you're diagnosed with candida hypersensitivity syndrome, the
practitioner may suggest you follow a restrictive diet that excludes
foods containing yeast, such as bread. You may also be asked to
eliminate sugar on the grounds that it encourages the growth of
yeast. Some treatments require you to take unnecessary antifungal
drugs, a practice that conventional doctors condemn because it
can cause such serious side effects as liver damage.
Elimination diets: If a CAM test indicates that you have multiple food allergies,
CAM practitioners may recommend eliminating many types of food.
Since this can lead to poor nutrition, they may also recommend
a diet that allows a single serving of a suspect food only once
every four or five days (a rotary diversified diet).
Endpoint titration
immunotherapy: This treatment is based on skin endpoint
titration testing. The CAM practitioner injects extracts of suspected
allergens under your skin with the goal of eventually desensitizing
you to them. Although this treatment is sometimes called optimal-dose
immunotherapy, the treatment dose has been proven to be far too
low to be effective.
Enzyme potentiated
desensitization: A very low dose of an allergen such
as pollen is mixed with a protein molecule (enzyme) and injected
under your skin. The enzyme theoretically prevents your immune
system from overreacting to the allergen. A single injection is
supposedly effective for an entire allergy season.
Extreme environmental
avoidance: Although avoidance of known allergens, such
as cat dander, is an accepted method of conventional allergy control,
CAM practitioners take avoidance to extremes. They claim that
allergens are numerous and widespread. So, for example, they may
advise you to completely remodel your home to make it safe from
chemical contaminants, move to an isolated community with low
pollution levels or wear a mask in public. Although some environmental
restrictions make sense for allergic people, such extreme measures
will not be a cost effective approach since true avoidance of
many allergens is often impossible.
Herbs and dietary
supplements: CAM practitioners claim that certain herbs
and dietary supplements mimic the effect of conventional allergy
treatments. Examples include bitter orange, country mallow, echinacea,
ephedra, grape seed extract, pycnogenol, quercitin, spirulina,
stinging nettle, thymus extract and vitamin C. No evidence shows
that these herbs and supplements work as well as prescription
drugs or immunotherapy. Some may be dangerous, particularly when
consumed in excess. For example, the Food and Drug Administration
banned ephedra in 2003 because it increases the risk of heart
attack, seizure, stroke and sudden death. And since Echinacea
is a member of the ragweed family, it might actually worsen your
allergies. Finally, the herbal supplement industry is not monitored
closely like the drug industry. Studies have shown, for example,
that Echinacea supplements from different companies may contain
no Echinacea at all while others are contaminated by a wide range
of plants and other substances.
Homeopathy: Homeopathic remedies are over-the-counter tablets containing extremely
diluted plant and animal extracts. The extracts are chosen because
they supposedly cause the same symptoms they're meant to relieve.
Since onions make eyes water, for example, onion extracts are
used in hay fever remedies. These approaches also have no experimental
evidence to support their use.
Neutralization therapy: Based on provocation-neutralization testing, neutralization therapy
aims to relieve allergy symptoms with injections or under-the-tongue
drops of neutralizing substances. Such substances include extracts
of known allergens, chemicals and foods. Again, there is a total
lack of data to support this approach and their practitioners
rely on testimonials for support.
It's possible that some CAM allergy approaches
may someday be proven safe and effective. But until then, the scientific
evidence overwhelmingly favors conventional allergy tests and treatments.
If a conventional treatment doesn't relieve your symptoms, keep
working with your doctor until you find a treatment that does.

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